加入收藏
百奥莱博公司客服电话百奥莱博QQ百奥莱博QQ百奥莱博QQ
百奥莱博公司微信服务号

产品目录

RKIP/PEBP1抗体图片
产品货号:
Z39472
中文名称:
RKIP/PEBP1抗体
英文名称:
Anti-RKIP/PEBP1 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-RKIP/PEBP1 Antibody
指标别名HCNP;HCNPpp;Neuropolypeptide h3;PBP;PEBP;PEBP 1;PEBP1;Prostatic binding protein;Raf kinase inhibitor protein;RKIP
克隆性Monoclonal
检验物种human,mouse,rat
应用范围WB,IHC,ICC/IF
基因名称PEBP1
抗体来源Rabbit
抗体类型IgG
免疫原A synthesized peptide derived from human PEBP1
实际分子量21KD
成分500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol.
纯化方式Affinity-chromatography
浓度500μg/mL
产品形态溶液
保存条件12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing.
背景资料PEBP1(Phosphatidylethanolamine-binding protein 1),also called PBP,RKIP,inhibits the phosphorylation and activation of MEK by RAF1.PEBP1 is identical to the phosphatidylethanolamine-binding protein(PBP) with a relative molecular mass of 23kD.The PEBP1 gene is mapped on 12q24.23.PEBP1 coimmunoprecipitates with RAF1 and MEK from cell lysates and colocalizes with RAF1 when examined by confocal microscopy.PEBP1 overexpression interferes with the activation of MEK and ERK,induction of AP1-dependent reporter genes,and transformation elicited by an oncogenically activated RAF1 kinase.PEBP1 expression was rapidly upregulated during induction of chemotherapy-triggered apoptosis in human prostate and breast cancer cell lines,and maximal RKIP expression correlated perfectly with the onset of apoptosis by Chatterjee et al(2004).RKIP depletion decreased the mitotic index,the number of metaphase cells,traversal times from nuclear envelope breakdown to anaphase,and an override of mitotic checkpoints induced by spindle poisons.
Uniprot IDP30086
基因名全称Phosphatidylethanolamine-binding protein 1
推荐稀释比
Western blot (WB) 1:500~2000
Immunohistochemistry in paraffin section (IHC) 1:20~100
Immunocytochemistry/Immunofluorescence(ICC/IF) 1:20~100

相关搜索:RKIP/PEBP1抗体RKIP抗体PEBP1单抗Anti-RKIP/PEBP1 Antibody
首页 |  关于我们 |  联系我们 |  在线咨询 |  网站地图
北京百奥莱博科技有限公司 京ICP备14007103号-3